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Systemic Targeted Radiation Therapy (STaRT)
Systemic Targeted Radiation Therapy (STaRT) is the use of radioactive isotopes that can travel throughout the body to treat certain cancers either ingested orally or via intravenous injection or infusion. Radioimmunotherapy (RIT) is a form of systemic radiation therapy that uses radiolabeled antibodies to deliver radiation directly to a tumor. Certain systemic radiopharmaceuticals are tumor or organ specific and are used to treat a variety of conditions including benign and malignant diseases as well as for cure and for palliation.
What conditions can STaRT treat?
Benign Diseases (Non-malignant conditions):
- Hyperthyroidism (Grave’s disease)
- Multinodular Goiter (enlarged thyroid with multiple nodules)
Malignant Conditions:
- Recurrent, relapsed or refractory low-grade, follicular, or transformed Non-Hodgkin’s Lymphoma (NHL). CD20 antigen-expressing and including Rituximab-refractory NHL.
- Thyroid Cancer
- Metastatic bone cancer from prostate, breast, or lung.
What isotopes or radiopharmaceuticals are used?
- Iodine-131 (I131) is used to treat thyroid conditions such as hyperthyroidism, multinodular goiter, and thyroid cancer.
- Zevalin® (90Yttrium Ibritumomab Tiuxitan) and Bexxar® (Iodine131 Tositumomab) are used to treat relapsed or refractory Non-Hodgkin’s Lymphoma.
- Strontium (SR89) and Quadramet™ (Samarium-153 Lexidronam are used to treat for palliation or pain relief from bony metastases.
Ask your Cancer Care Consultant physician if you are a candidate for STaRT.
For more information visit:
http://www.QUADRAMET.com
http://www.ZEVALIN.com
http://www.BEXXAR.com
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